The adiponectin test is a blood test that measures the level of adiponectin, a hormone (also called an adipokine) produced primarily by fat cells (adipose tissue). Adiponectin plays an important role in regulating metabolism, insulin sensitivity, inflammation, and fat breakdown.

What the adiponectin test measures

The test measures the amount of adiponectin circulating in the blood. In general:

• Higher adiponectin levels are often associated with better insulin sensitivity and a lower risk of metabolic complications.

• Lower adiponectin levels are often associated with insulin resistance, obesity, and increased risk of metabolic disorders.

What it may help evaluate

Adiponectin testing may be used in research or specialized clinical settings to assess risk or monitor conditions such as:

• Insulin resistance

• Type 2 diabetes risk

• Metabolic syndrome

• Obesity-related metabolic changes

• Cardiovascular disease risk

• Inflammation and changes in fat metabolism

Factors that can affect adiponectin levels

Adiponectin levels may be influenced by:

• Body weight and body fat distribution

• Physical activity

• Diet

• Age

• Hormonal factors

• Certain medications

• Metabolic conditions